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However, this efficacy came with trade-offs

130,134,135 It happens in hypoxic regions of tumor regression and increases invasion and metastasis in mouse models of pancreatic neuroendocrine carcinoma and glioblastoma (GBM)

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They are approved for managing type 2 diabetes and weight-related conditions, and any mental health benefits are likely secondary to metabolic improvements rather than direct anxiolytic effects

Hollywood-hyped fixes for weight are a dime a dozen