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The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione

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17 The increased systemic oxidative stress in disease progression and its association with other oxidative stress-related pathologic conditions were suggested for further studies

Moving forward, robust longitudinal clinical studies, mechanistic elucidation, and personalized microbiome profiling will be critical to transforming this emerging science into actionable therapies for neurodegenerative disease