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Gutierrez-Mariscal FM et al

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Introduction Getting a sudden infection while you are on a consistent health journey can feel like an unwanted roadblock

Beyond their well-established benefits in managing type 2 diabetes mellitus (T2DM) and promoting weight reduction, emerging evidence suggests that GLP-1 RAs may also offer neuroprotective, anti-inflammatory, and cardiovascular protective effects 4,5,6,7

Chugai's medicinal chemistry team identified a series of small molecules that could activate the GLP-1 receptor through an unconventional binding mode