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Lipid quality control and ferroptosis: from concept to mechanism

(n = 3)

Zebrafish share 80% of human disease genes, and their early embryos lack adaptive immunity, permitting xenotransplantation of human tumor cells without immunosuppression (Molina et al., 2021)

Oka A, Takagi A, Komiyama E, Yoshihara N, Mano S, Hosomichi K, Suzuki S, Haida Y, Motosugi N, Hatanaka T, Kimura M, Ueda MT, Nakagawa S, Miura H, Ohtsuka M, Tanaka M, Komiyama T, Otomo A, Hadano S, Mabuchi T, Beck S, Inoko H, Ikeda S (2020) Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss

An insulin hypersecretion phenotype precedes pancreatic cell failure in MODY3 patient-specific cells