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We are also recommending that if patients are starting these drugs or increasing the dose of these drugs, they should do so slowly to reduce the risk of dropping their blood sugar and causing an osmotic shift. Bradley Katz, MD, PhD We as well as other concerned physicians are also asking FDA to mandate a post-marketing survey of these drugs to find the true incidence of eye complications associated with them

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Both figures come from peer-reviewed NEJM trials of FDA-approved active ingredients in controlled settings - not from compounded formulations or any specific platform

DOI: 10.1136/bmjebm-2022-112231