Published 2022 Nov 7
Int J Mol Sci 22:4416 Op den Kamp YJM, de Ligt M, Dautzenberg B, Kornips E, Esterline R, Hesselink MKC, Hoeks J, Schrauwen-Hinderling VB, Havekes B, Oscarsson J, Phielix E, Schrauwen P (2021) Effects of the SGLT2 inhibitor dapagliflozin on energy metabolism in patients with type 2 diabetes: a randomized, double-blind crossover trial
10.1111/apt.16608 20 GaoZ.SongG.-Y.RenL.-P.MaH.-J.MaB.-Q.ChenS.-C
Gastrointestinal Side Effects Frequency Nausea, diarrhea, vomiting, and constipation are generally reported more frequently and intensely than flatulence, but gas is still a noteworthy part of the GI side effect mix
The timeline for sphincter improvement in animal studies varies based on administration route and severity of dysfunction