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Here are some ways it functions: 1

Alternatively, it could be assumed that even increased levels of gut GLP1 do not reach these areas under physiological conditions and, although innervation from PPGs might be sparse, it might be sufficient to provide synaptic/local GLP1 signalling physiologically or pathophysiologically

it changes outcomes

These changes were partially moderated by changes in brain morphometry, underscoring the interrelationship between weight and brain structure/ function

Allison Rhodes, a primary care physician with dual board certifications in internal medicine and obesity medicine at The Ohio State University Wexner Medical Center in Columbus