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The elevated GSH liver concentrations observed in the group treated with free GSH (group II) would help to accelerate the restoration of mitochondrial GSH levels and inactivate the reactive species formed at this stage, thereby limiting hepatocellular necrosis

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However, this effect was not observed in rats treated with estradiol alone

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American Society for Metabolic and Bariatric Surgery Integrated Health Nutritional Guidelines for the Surgical Weight Loss Patient 2016 Update: micronutrients