glutathione peroxidase and glutathione reductase Redox cycles linking metabolic antioxidant pathways. Reactive oxygen species, toxicity, oxidative

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Zhang Y, Liu Y, Liu H, Tang W

Key Points The insulin-like growth factor 1 ( IGF1 ) gene is a major target of growth hormone IGF1 binds the IGF1 receptor (IGF1R) with high affinity and the insulin receptor with low affinity

182 Under normal healing conditions, immunomodulation controls these inflammatory cascades, enabling following regeneration cascades led by anti-inflammatory cytokines to advance the wound toward complete healing

Des travaux rcents suggrent une interaction avec la voie JAK-2/STAT-3, implique dans la rponse inflammatoire et la survie cellulaire, renforant l'hypothse d'un mcanisme d'action pliotrope