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Skin lightening was noticed in a patient as a side effect of large doses of glutathione, which was given for some other disease, and then onwards, it became more popular as a skin lightening agent
Francois de la Peyronie first described the condition in 1743 while he was the surgeon for Louis XIV of France
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Still, the convergence of animal studies, observational data, and early clinical trials makes this one of the most intriguing new directions in addiction research
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