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Using too much does not necessarily enhance the effectiveness and could potentially lead to irritation

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Wolfrum C, Borrmann CM, Borchers T, Spener F (2001) Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alphaand gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus

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10.1007/s12640-019-0003-y 46 RamalhoM.FontesF.RuanoL.PereiraS.LunetN