Anthracyclines such as doxorubicin and epirubicin cause cell death and cytotoxicity by intercalating into DNA and disrupting replication, this is part of standard treatment (215)
Elmansour I, Chiheb S, Benchikhi H
Promotion of neuronal survival and regeneration By activating the Brain-derived neurotrophic factor/tropomyosin receptor kinase B (BDNF-TrkB) signaling pathway, Rg1 can protect neurons against degeneration while controlling synaptic plasticity (Zhong et al., 2020)
These essential co-enzymes function as energy transducers, signalling molecules, and redox couples, the balance between the oxidized and reduced forms being important in the maintenance of cellular redox status, regulation of ion channels, and responses to environmental and metabolic challenges that determine cell fate (Noctor et al
In the current analysis, published in Nature Medicine , Aminian and colleagues followed adults with type 2 diabetes and obesity who either underwent bariatric surgery (n = 1,657) or received GLP-1s (n = 2,275) for up to 10 years