does semaglutide affect the pancreas Wegovy and Acute Pancreatitis Likely Due to

Sean Wharton, leader of the Wharton Medical Clinic for Weight and Diabetes Management in Ontario, Canada

It currently makes three drugs that contain semaglutide, including: Wegovy, a once-weekly injectable medicine for weight loss and cardiovascular risk reduction Ozempic, a once-weekly injectable medicine for Type 2 diabetes and cardiovascular risk reduction, often prescribed off-label (for a non-FDA-approved use) for weight loss Rybelsus, a daily oral medicine for managing blood sugar levels in people with Type 2 diabetes, and sometimes prescribed off-label for weight loss These three brand-name medicines are the only FDA-approved semaglutide products

Herrington WG, Staplin N, Wanner C et al (2023) Empagliflozin in patients with chronic kidney disease

What we do not know yet Long-term incidence rates over 1 to 2+ years of continuous use

The drug includes small changes to its structure to make it more stable and less likely to be broken down by enzymes