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The study concluded that the GLP-1 medication liraglutide was among the most effective pharmacological weight loss treatments

However, given the large and growing body of preclinical literature highlighting mechanisms outside of body weight contributing to sex differences in effects of GLP-1R agonism (eg, interactions with estrogen), the case for meaningful and potentially clinically relevant differences remains, if not strong, then at least certainly warranting careful attention to sex as an important variable in GLP-1 system research

Some promising studies for heart failure, muscle pain from statins, and exercise performance, but less consistent results for prevention or anti-aging effects

El Eid L, Reynolds CA, Tomas A, et al

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