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Compared with GLP-1 receptor agonists, the GLP-1 receptor agonistSGLT-2 inhibitor combination was associated with a 39% lower risk of major adverse liver outcomes [HR 0.61 (95% CI 0.490.77)] and a 35% lower risk of major adverse cardiovascular events [HR 0.65 (0.600.70)] during a median follow-up of 6.3 months

Its expected to extend Lillys lead in diabetes treatments with Mounjaro and in obesity with Zepbound

These early non-responders often exit programs within the first few weeks, citing failure to achieve the expected goal and expressing feelings of frustration and disappointment

Seeking alpha Although no consensus on noninvasive measures for NASH has been reached, histological evaluations of steatosis, inflammation, hepatocyte morphology, and fibrosis are well accepted