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It could be heavy metals, non-metal toxins, mold toxins, or a combination

Changes in microbial makeup can lead to inflammation and disease development [21]

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Gut microbial metabolic processes of dietary polyphenols and procyanidins have been detailed in various reviews ( 6.1 Pre-systemic metabolism: role of gut microbiota Although some oligomeric or polymeric procyanidins might be already subjected to microbial metabolism in the small intestine (78)