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5-Amino-1MQ operates through NNMT inhibition

For example, controlled trials in diabetic polyneuropathy have employed 600 mg of ALA injected IV once daily (often given as an infusion over 30-60 minutes) for periods of 2-4 weeks, with significant efficacy observed in reducing neuropathic symptoms compared to placebo

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Glutathione has been reported as essential element to counteract negative influences