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Essential role of insulin-like growth factor-1 in the intestinal tropic effects of glucagon-like peptide-2 in mice

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In cases where extensive resection will not cause severe defects, it should include the removal of adjacent tissues to reduce the likelihood of malignant transformation and metastasis

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The incidence of malformations exceeded concurrent and historical controls at 0.01 mg/kg/day (kidneys, scapula), 0.01 mg/kg/day (eyes, forelimb), 0.025 mg/kg/day (brain, tail and sacral vertebrae, major blood vessels and heart, umbilicus), 0.025 mg/kg/day (sternum) and at 0.05 mg/kg/day (parietal bones, major blood vessels)