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sUA and MSU crystals regulate monocyte MSU crystals induce monocyte-associated inflammation.MSU crystals directly instigate the assembly of NLRP3 inflammasome in monocytes, leading to an increase in IL-1 production (25, 26)

The relevant question for cagrilintide is whether an amylin analog engineered for tonic, week-long receptor occupancy follows the same pattern

The serum antioxidant ability is remarkably enhanced after APP treatment, which is closely related to the up-regulated serum GSH level, GSH/GSSG ratio and antioxidant enzyme activities after APP treatment

10.1084/jem.103.5.589