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In the PPAR agonist experiments, mice were intraperitoneally injected with WY14643 at 50 mg/kg (dissolved in 100 L of 10% DMSO and 90% corn oil) daily for 5 days

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The SUMMIT trial, conducted by Eli Lilly and published in November 2024, focused on 731 patients with both heart failure (ejection fraction 50%) and obesity

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