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Accessed January 11, 2008

The investigators measured how the smokers smoked each of the products, the exhalation of carbon monoxide and their craving and withdrawal symptoms

Despite all studies consistently indicating a statistically significant positive association between exclusive e-cigarette use and the odds of having COPD, the selected studies exhibited high heterogeneity ( I 2 = 91.02%), and the prediction interval for the ORs was 0.73 to 5.97 (Figure 3A)