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Covariate definitions Baseline waist circumference, systolic and diastolic blood pressure, fasting glucose, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride, estimated glomerular filtration rate, and dipstick urine albumin measurements were collected from the NHSP

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American Spirit cigarettes contain higher nicotine levels, with an average of 3.3 mg per cigarette compared to 2.4 mg in other brands