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Verzenio was approved to be given with hormonal therapy for two years if the cancer has clinical and pathological signs that indicate a high risk of recurrence and has Ki67 levels of 20% or higher, determined using a companion diagnostic test that was approved along with this use

The latter are critical to gene expression of pro-inflammatory mediators such as interleukin (IL)-8, IL-6, and tumor necrosis factor- (TNF-) which links cigarette smoke exposure with altered cytokine production [90]

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-CNBC's David Faber contributed to this report