REAL WORLD EVIDENCE: NEW ZEALAND + JAPAN In 2019, five years after heated tobacco products were first introduced in Japan, a study conducted by researchers working for the American Cancer Society found an unprecedented decline in cigarette sales in the country
Consequently, most assessments of human exposure to trace levels of environmental chemicals are inaccurate
In 2012, five retailers were caught selling tobacco products to decoys deputies posing as minors, including Ralphs at The Commons, Oaks Shell on Mulholland Highway and 7-Eleven on Las Virgenes Road
On long-term effects: synthetic nicotine itself isnt new chemistry, but its use at scale in consumer products is recent enough that we dont have multi-decade epidemiological data were relying on toxicology and on the fact that nicotine itself, as opposed to combustion products, has a fairly well-understood risk profile
This evidence suggests a causal effect 6,7