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This damages cells and genetic material, increasing the risk of chronic conditions like COPD and lung cancer

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Gene polymorphisms, and epigenetic changes including DNA methylation, histone modifications and non-coding RNAs, may play a role in susceptibility and abnormal repair following epithelial injury in COPD (152, 177)

Moist snuff containers weighing more than 1.2 ounces are taxed at the greater of 95% of the wholesale price or a minimum tax equal to the cigarette tax on each container multiplied by the number of ounces of moist snuff in the container, divided by 1.2 (container = smallest consumer-size can, package or other container that is marketed or packaged by an entity for separate sale to a retail purchaser)

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