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Exposure to EC aerosols enhanced susceptibility to infection, as shown by increased inflammatory responses in Porphyromonas gingivalis- and Fusobacterium nucleatum- challenged epithelial and malignant cell lines, highlighting a dysbiotic microbiome and immune dysregulation in EC users [61]

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In the USA, simulations based on the three fire emissions had comparable performance against ground observations, with R between 0.46 and 0.47