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The neurotransmitter systems affected by cigarette smoke mirror the neurotransmitter pathways that are thought to be involved in the biological mechanisms of depression, and the use of antidepressants as adjuvants to smoking-cessation treatment can enhance cessation success rates

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Reeve died on March 6, 2006, at the age of 44, 11 days before her 45th birthday at Memorial SloanKettering Cancer Center in New York City

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