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Philip Morris faced a lawsuit in the EU for involvement in organised crime in pursuit of a massive, ongoing smuggling scheme ; and Canada filed a racketeering and smuggling lawsuit against RJ Reynolds, to the tune of $1 billion

27 Moreover, widely used pharmacological treatments such as systemic corticosteroids may induce hyperglycemia, while -agonists and anticholinergics can influence glucose handling through effects on glycogenolysis, insulin secretion, and cellular uptake

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