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Tobacco was so generally liked that no legislative measures could prevent its use." At first the use of tobacco was confined to fops and the hangers on at ale houses and taverns but afterwards by the "chief men of the realm." Soon after the importation of the "durned weed" from Virginia the tobacco muse gave forth many a lay concerning the custom

When LES pressure decreases, stomach acid can easily flow up into the esophagus, leading to acid reflux

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plant (for example, in North Carolina)

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