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Similar results were also identified in lung epithelial cells exposed to various flavor additives such as acetoin (sweet and buttery), orthovanillin (vanilla), and cinnamaldehyde (cinnamon), which exhibited an increase in proinflammatory cytokines synthesis [59]

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For example, nearly two-thirds of the population live in a state or community with a comprehensive smoke-free policy that prohibits smoking in all indoor areas

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In the United States, from the 1950s until the 1990s, tobacco industries wielded great influence in shaping public opinion on the health risks of tobacco