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30,31 Sucralose degradation at 350400 C can yield polychlorinated dioxins and furans, with reactions catalyzed by metals (Al, Fe, Cu, etc.) and metal oxides, found in tobacco products including some e-cigarette and e-hookah heating coils

The rate of decline then slowed, with smoking prevalence falling by only about one percentage point every two years until 1994, after which it stabilized at about 27% before resuming a slow decline in the first decade of the twenty-first century [ 25 ]

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National Institutes of Health