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The reinforcing effect and DA level induced by DNC + NIC were greater than the sum of the two parts, suggesting that the relationship of the DNC group to nicotine was synergistic rather than additive, and the synergistic effect was further supported by the unique enhancement of the DNC + NIC group in locomotor activity compared to the NIC group (Figure 2C) and anxiety performance (Figure 2D)

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But when we play live, theres this contrast between how mellow we are on stage and the hysteria of people screaming the lyrics where there's a lot of intense, raw motion being thrown around

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The versions of the character played by Andrew Garfield and Tom Holland would not have this side effect