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Farsalinos does a great job of explaining what they really mean: This methodology suffers from a major problem, the Greek scientist writes on his blog

Serum cotinine, a primary metabolite of nicotine, is directly proportional to the extent of tobacco smoke exposure and can serve as a reliable indicator of smoking intensity and tobacco smoke exposure 18,19

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Id pick Portrait of a lady rather than this

citizen whose car was fired on by agents in San Bernardino, California