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With respect to those assays which are used to investigate cytotoxicity (Neutral Red uptake assay), several heated tobacco products including the EHCSS, EHCSS Series K, THS 2.2 and THP 1.0 have been assessed using this assay (Tewes et al., 2003

The study included more than 800 high schoolers from three public schools in Connecticut

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The toxins from cigarette smoke are also swallowed into the gut