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Its interesting from a scientific standpoint, but boy does it complicate the public health messaging. Prior to the CANDIDE study, Springer and his UCSF research group had done many studies in rats, which have similar cardiovascular responses to tobacco smoke as humans do, and which can be studied under tightly controlled experimental conditions

"Since smoking exposes the entire body to the tobacco compounds that inhibit MAO B, we believed it had the potential to limit MAO B activity throughout the body," said Fowler, who conducted the current study to investigate this effect

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