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Smaller devices like this have very low CADR and small amounts of carbon so will lose effectiveness quickly with a pollutant like cigarette smoke

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And while the AD4000 is made for larger spaces, if one wanted to achieve the four air exchanges per hour that the AD4000 supposedly can do, then it would have its fan at the highest setting

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Nicotine has significant biologic activity and adversely affects several physiological systems including the cardiovascular, respiratory, immunological and reproductive systems, and can also compromise lung and kidney function [41]