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The role of manganese dysregulation in neurological disease: emerging evidence

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Stage 1 Duration: Day 1-2 Contagiousness: Low Symptoms: Tingling or itching sensation around the lips or mouth Experiencing a tingling or itching sensation around the lips or mouth is the first indication that a cold sore outbreak is imminent [2] , although there may be no visible signs of a cold sore at this point

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