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[31] Repeated exposure to nicotine can cause an increase in the number of nicotinic receptors, which is believed to be a result of receptor desensitization and subsequent receptor upregulation
15, 16 Flavorings in e-cigarette liquids are also shown to be harmful when inhaled and can inflame and damage the airway and lung tissue
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They will especially overwinter directly in the fields of tobacco if plant stalks were not removed following harvest
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