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In the study, published in the journal iScience, Soumita Das, PhD, associate professor of pathology, and Pradipta Ghosh, MD, professor of cellular and molecular medicine at UC San Diego School of Medicine and Moores Cancer Center at UC San Diego School of Medicine, with colleagues, found that chronic use of nicotine-free e-cigarettes led to a leaky gut, in which microbes and other molecules seep out of the intestines, resulting in chronic inflammation

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It is also associated with an increased chance of quitting and a reduced risk of relapse among former smokers.[4]