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Tobacco use continues to be one of Canada's most significant public health problems and is the country's leading preventable cause of disease and premature death, Health Minister Jean-Yves Duclos said

Harm reduction does not focus primarily on the eradication of products or behaviours | KAC, UK Updated November 202 5

These findings suggest that women in particular may be at greater risk because they accumulate higher concentrations of cancer causing chemicals in their body whether they smoke roll-your-own or manufactured cigarettes