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While the rate of acetylation does not significantly impact the drugs effectiveness, it may result in elevated levels of INH in the bloodstream and a higher occurrence of ADRs

Indeed, the large increases in tobacco taxation over the previous decade has been accompanied by substantial growth in the supply and use of illicit tobacco products, with the Australian Tax Office estimating that, as a proportion of the total of the tobacco market, the illicit market increased from 4.9% in 2014-15 to 14.3% in 2022-23 [43]

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