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Ethic Statement This study has been approved by our institutional ethics committee for animal experiment of Aix-Marseille University (Comit dEthique de Marseille

Knowing that pregnancy nicotine use is super risky, knowing that nearly all population-level findings suggest that OTC NRT is ineffective and that the vast majority of UK smokers who successfully arrest their dependence upon nicotine do so cold turkey, why aren't these 18 researchers super driven to investigate, discover and share the "preferable" keys to successful abrupt nicotine cessation

While the chemicals in cigarette smoke cause blood vessels to narrow, nicotine raises blood pressure and heart rate, this restricts blood flow and increases the risk of clotting

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