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These findings were supported by the subjective response questionnaires, which showed that the THPs were non-inferior to the NRT inhaler in terms of PLQ and OIUA scores, and superior to the NRT inhaler in terms of UFP score

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Furthermore, clinical trials have shown that standard NRT doses are inadequate for rapid metabolizers of nicotine (i.e., those who inactivate nicotine to cotinine and then to 3-hydroxycotinine [3-HC] more quickly than others due to genetic variation affecting the activity of the hepatic enzyme CYP2A6) [20, 25]

The first day in makeup took eight hours, he continued