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One limitation of our study is the extrapolation of data from mouse models to human COPD progression, as differences in respiratory systems and immune responses between species can affect the applicability of these findings to humans

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Reduced chronic toxicity and carcinogenicity in A/J mice in response to life-time exposure to aerosol from a heated tobacco product compared with cigarette smoke

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Its been shown that kids are more susceptible to addiction and that products like the nicotine-free vape are marketed toward them, leading to much easier development of addiction