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Issue 5

Nicotine has known pathological effects, mainly related to the excessive release of catecholamines, endothelial dysregulation and increased insulin resistance.90 Nicotine in electronic cigarettes has been shown to increase heart rate after overnight abstinence.91 Regarding lipid metabolism, nicotine in electronic cigarettes has been shown to increase the amount of circulating saturated fatty acids, decreasing the content of unsaturated fatty acids and inducing insulin resistance

95% CI 0.74 to 0.89), especially in all cancer (HR 0.84

I never made it more than a couple of days before giving in, crying, overwhelmed with relief and self-loathing

Smoking should never be used as a weight loss strategy, as it poses serious health risks and consequences