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Second, the study did not incorporate pharmacokinetic profiling, which limits our ability to fully explain whether reductions in nicotine and cotinine levels were due to altered metabolism, distribution, or clearance mechanisms

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However, studies have shown that AT-LDL levels decrease significantly within three months after quitting smoking

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E-cigarette use may increase the risk of cardiovascular problems, such as heart attacks and strokes as well as other health risks at the same level as smoking cigarettes