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Because these drugs are not tested under laboratory conditions, not manufactured under professional quality control conditions, and distributed illicitly, numerous problems can occur that can include an increased risk for brain damage, an increased risk for stroke or heart damage, and an increased risk for other detrimental effects that can affect the muscular system

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Nicotine and 6MN as well as 2MN, 4MN, and 5MN have two enantiomeric forms each, S and R