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A recent longitudinal cohort study ( n = 100 cases, 100 controls) by Howell et al., for example, found prenatal maternal tobacco smoking to be a predictor of childhood ADHD and to be associated with shortened infant telomere length when controlling for maternal depression [ n = 19,940) found that maternal smoking increased ones risk for ADHD by 2.64 times (95% CI 1.454.80) and paternal smoking during pregnancy to increase ones risk for ADHD by 1.17 times (95% CI 1.981.39) [70]