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A summary of all the research done thus far concluded that the nicotine content of e-cigarettes varies widely between products, and the amount of nicotine a person inhales increases with higher-powered devices that heat the liquid to a higher temperature

Thus, a systems toxicology meta-analysis concluded that IQOS has reduced and more transient effects than CS on buccal, nasal, and bronchial epithelial cells regarding xenobiotic metabolism, oxidative stress, and inflammatory responses 63

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Cytokine 153 , 155828 (2022)