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More than 7 million deaths occur due to direct tobacco consumption

With the proposed sample size, we will have sufficient power to detect a similar or smaller effect in the range of medium-to-large effect sizes (Cohens d = 0.64, Cohens f = 0.32) with 80% power at two-sided alpha level of 0.05 for the interactions of interest

For daily toothpaste, many brands prefer a safer and easier message: surface stain removal, fresh breath, and daily oral hygiene

The years not won by a Tobacco Road team are 1987, 2004, 2011, 2012, and 2013

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